About the role#
The non-clinical bioanalysis team within the Translational Medicine Unit at Sanofi is seeking a co-op for Winter 2027. This role focuses on developing bioanalytical assays to understand pharmacokinetics and pharmacodynamics to support discovery and preclinical studies. You will work alongside experienced teams to develop LC-MS-based methods and contribute to scientific discussions regarding drug development.
What you'll do#
- Design and qualify PK LC-MS assays for biologics and antibody oligonucleotide conjugates.
- Develop sample preparation methods including protein precipitation, solid phase extraction, immunoprecipitation, and enzymatic digestions.
- Utilize LC-MS/MS and LC-HRMS for intact protein, middle-up, and bottom-up analysis.
- Characterize the pharmacokinetic profile of constructs, including integrity analysis.
- Analyze samples to support pharmacokinetic and pharmacodynamic studies.
- Report and discuss bioanalytical and biomarker results.
What you'll need#
- Currently pursuing a PhD in biochemistry, biotechnology, pharmaceutical sciences, or related health sciences with a graduation date no later than December 2028.
- Enrollment in an accredited college or university for the duration of the co-op.
- Permanent authorization to work in the U.S. without the need for sponsorship.
- Expertise in high-resolution mass spectrometry or triple quadrupole mass spectrometry.
- Proficiency with Thermo, Waters, or Sciex platforms for protein analysis.
- Experience with protein quantitation extraction techniques in biological matrices.
- Knowledge of proteomics tools, such as protein database queries and sequence analysis.
- Understanding of pharmacokinetics and pharmacodynamics concepts.
- Preferred: Experience with AI tools for drug discovery, strong problem-solving skills, and good communication abilities.
Location & details#
- Location: Cambridge, Massachusetts.
- Modality: On-site.
- Schedule: 40 hours per week, Monday through Friday.
- Compensation: $57 per hour.
- Duration: 6 months.
About Sanofi
Sanofi is a pharmaceutical manufacturing company based in Paris, France. It employs over 93,000 people across global offices. The company focuses on vaccines, rare diseases, neurology, immunology, and oncology. It also operates in the fields of diabetes, cardiovascular diseases, and consumer healthcare.
How to get in at Sanofi
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