Metaphore Biotechnologies: Analytical Characterization / Protein Science Co-Op

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    Flagship Pioneering

    We are a biotechnology company that invents and builds platform companies that change the world.

    501-1,000 employeesFounded 2000Cambridge, MABiotechnology Research
    Actively hiringPaidWinter 2027Biotechnology Research
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    Best applied by Oct 6

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    About the role#

    This co-op position is open to current Northeastern University students. You will join the Protein Science team at Metaphore Biotechnologies for a full-time, on-site engagement from January 2027 to June 2027. You will contribute to the Developability Program by performing hands-on experimental work, supporting analytical assay development, and synthesizing data to inform scientific decision-making.

    What you'll do#

    • Develop and optimize analytical assays to support company programs.
    • Execute and analyze data from a suite of analytical assays, including QC and kinetics or affinity assessments.
    • Contribute to the development and implementation of UPLC-based separation methods, such as Reversed Phase, Hydrophobic Interaction Chromatography, and Ion-Exchange Chromatography.
    • Research and develop methods for developability assessments, including AC-SINS, ELISA, and Poly-reactivity.
    • Draft and update protocols, SOPs, and Benchling templates.

    What you'll need#

    • Current pursuit of a degree in Biochemistry, Biology, Chemistry, Bioengineering, or a related field.
    • Strong organizational skills and attention to detail for documentation and tracking.
    • Ability to analyze large data sets, identify patterns, and draw conclusions.
    • Critical thinking and proactive problem-solving skills.
    • Curiosity and a strong desire to learn.
    • Experience with analytical techniques like HPLC/UPLC separation, thermal stability assessment (DLS, nanoDSF), and binding or affinity assessment (BLI or SPR) is preferred.
    • Familiarity with SDS-PAGE and plate-based assays (ELISA) is preferred.
    • Experience in wet lab techniques, such as pipetting, is preferred.

    Location & details#

    • Location: Cambridge, Massachusetts.
    • Term: Winter 2027 (January to June).
    • Modality: Full-time, 40 hours per week, 5 days per week on-site.
    • Compensation: $25 to $35 per hour.

    About Flagship Pioneering

    Flagship Pioneering is a biotechnology firm based in Cambridge, Massachusetts. Founded in 2000, the company focuses on inventing and building platform companies that develop products for human health and sustainability. It has originated more than 100 scientific ventures since its inception. The current ecosystem includes over 40 companies, such as Indigo Agriculture and Generate:Biomedicines.

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