Co-op, mRNA-LNP Therapeutics

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    Kernal Biologics

    KernalBio creates mRNA therapies that instruct specific cells on how to make their own medicine

    11-50 employeesFounded 2016Cambridge, MassachusettsBiotechnology Research
    Actively hiringPaidrollingBiotechnology Research
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    Best applied by Oct 10

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    About the role#

    Kernal Biologics is seeking a Co-op to join our LNP team in Boston. You will work on next-generation mRNA-LNP therapeutics by supporting production, analytical testing, and process development. This position provides hands-on experience in manufacturing functions while working alongside scientists and engineers. You will also help manage technical documentation such as protocols and batch records.

    What you'll do#

    • Support routine mRNA and LNP production, purification, and analytical testing.
    • Assist with LNP formulation, optimization, and scale-up.
    • Contribute to antibody-LNP conjugation and characterization workflows.
    • Develop analytical methods for mRNA-LNP products.
    • Maintain human and murine cell lines using sterile technique, including passaging, cell counting, and cryopreservation.
    • Transfect IVT and LNP-formulated mRNAs into mammalian cells and quantify expression via flow cytometry.
    • Draft and review SOPs, protocols, and batch records.
    • Maintain precise and organized laboratory records.
    • Collaborate across teams to share data and execute processes.

    What you'll need#

    • Current B.S. or M.S. student in Biology, Biomedical Engineering, Molecular Biology, Biochemistry, Pharmaceutical Sciences, or Analytical Chemistry.
    • Familiarity with mRNA/LNP unit operations like in vitro transcription, chromatography, and filtration.
    • Hands-on mammalian cell culture experience at the bench, including transfection and viability assays.
    • Experience with molecular biology techniques such as PCR, cloning, or gel electrophoresis.
    • Experience with flow cytometry is a plus.
    • At least 6 months of previous laboratory experience is strongly preferred.
    • Ability to work full-time (35-40 hours per week) on site for at least 6 months.
    • Reliability and attention to detail.

    Location & details#

    • Location: Boston, Massachusetts (Seaport).
    • Modality: On-site.
    • Commitment: Full-time (35-40 hours/week) for at least 6 months.
    • Compensation: Paid position.

    About Kernal Biologics

    Kernal Biologics is a biotechnology research company based in Cambridge, Massachusetts. Founded in 2016, the firm focuses on mRNA therapies designed to instruct cells to produce medicine for treating cancer and other severe diseases. The team maintains expertise in synthetic biology, RNA design, and immunotherapy. It currently operates with 21 employees.

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