About the role#
As a member of the protein engineering team at Serif Biomedicines, you will work at the intersection of computational protein design and wet-lab experimental validation. This position is open exclusively to current Northeastern University students. You will participate in the Flagship Pioneering Co-Op Program, which includes access to enrichment sessions and a dedicated professional development track.
What you'll do#
- Apply ML models of protein sequence and structure to engineer novel proteins with desired functions.
- Construct DNA libraries and transform them into yeast for functional analysis using FACS and flow cytometry.
- Coordinate the biophysical characterization of protein binders with third-party vendors.
- Analyze experimental results and communicate findings to the team.
- Collaborate with experienced scientists to iterate on laboratory protocols.
What you'll need#
- Currently pursuing a MS in Molecular Biology, Cell Biology, Bioengineering, Biochemistry, or a related field.
- Hands-on experience with core wet-lab techniques, including PCR, molecular cloning, and flow cytometry.
- Basic proficiency in a programming language used for data analysis, such as Python or R.
- Comfort working in command-line environments and experience with DNA sequence analysis.
- Strong organizational skills and attention to detail.
- Familiarity with ML architectures for protein engineering, such as AlphaFold or RFDiffusion, is a plus.
Location & details#
- Location: Cambridge, Massachusetts.
- Term: January 2027 to June 2027.
- Modality: Full-time, 40 hours per week, 5 days per week on-site.
- Compensation: $25 to $35 per hour.
- Note: This is a paid, short-term engagement and is not eligible for health and welfare benefits.
About Flagship Pioneering
Flagship Pioneering is a biotechnology firm based in Cambridge, Massachusetts. Founded in 2000, the company focuses on inventing and building platform companies that develop products for human health and sustainability. It has originated more than 100 scientific ventures since its inception. The current ecosystem includes over 40 companies, such as Indigo Agriculture and Generate:Biomedicines.
How to get in at Flagship Pioneering
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