About the role#
The Computational Toxicology group at Genentech is looking for a summer intern to help apply computational methods to target safety research. You will work within an interdisciplinary team to investigate biological systems relevant to preclinical safety assessment. This project uses single-cell transcriptomic and multi-omics data, alongside AI and machine learning, to address complex biological questions.
What you'll do#
- Develop reproducible computational workflows to integrate and analyze single-cell transcriptomic and multi-omics datasets.
- Characterize in vitro models and assess their biological relevance through quantitative analysis and comparisons with reference datasets.
- Explore and benchmark AI and machine learning methods, including foundation models, for analyzing high-dimensional biological data.
- Collaborate with computational and experimental scientists to interpret findings and build reusable analysis tools, including LLM-based or agentic workflows.
What you'll need#
- You must be an enrolled student pursuing a Master's degree or PhD, or have already attained a Master's degree.
- Degree background in Bioinformatics, Computational Biology, Bioengineering, Computer Science, Data Science, Statistics, Machine Learning, or a related field.
- Experience with Python or R for scientific data analysis and computational workflows.
- Familiarity with biological datasets, such as gene expression or other omics data, and associated metadata.
- Ability to quality-check, analyze, and interpret complex biological datasets.
- Experience documenting methods and maintaining reproducible analyses using version control tools.
- Strong problem-solving, communication, and teamwork skills.
- Familiarity with single-cell RNA-seq concepts and analysis tools like Scanpy, AnnData, Seurat, or scVI.
- Experience with differential expression, pathway analysis, or comparative transcriptomics.
- Interest in machine learning, representation learning, or foundation-model applications in biological research.
- Familiarity with LLM-based tools and agentic workflows.
Location & details#
- This internship is located on-site in South San Francisco, California.
- This is a full-time, 12-week summer position.
- The role is paid and includes paid holiday time off.
About Genentech
Genentech is a biotechnology research company founded in 1976. Based in South San Francisco, the firm focuses on areas such as oncology, neuroscience, and immunology. It employs over 18,000 people across multiple locations in California and Oregon. The organization develops medicines for complex health conditions.
How to get in at Genentech
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