Co-op Process and CMC Data Science

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    Sanofi

    10,001+ employeesParis, FrancePharmaceutical Manufacturing
    Actively hiringPaidWinter 2027Pharmaceutical Manufacturing
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    Best applied by Oct 25

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    About the role#

    This co-op position is based in the Data and Computational Science department within the mRNA Center of Excellence. You will work on developing models for drug-substance unit operations to help accelerate mRNA-based process development. This role offers hands-on experience with mRNA technology and biopharmaceutical manufacturing while applying advanced modeling techniques.

    What you'll do#

    • Develop and validate first-principle, machine learning, and hybrid models for unit operations including IVT, TFF, and Chromatography.
    • Investigate how process parameters affect critical quality attributes and quantify the associated uncertainties.
    • Design and execute Design of Experiments (DoE) for model structure selection, parameter estimation, and process optimization.
    • Analyze experimental and simulation data to generate insights for process development.
    • Document your modeling workflows, results, and recommendations in technical reports and presentations.

    What you'll need#

    • Current enrollment in a Master's or PhD program in Chemical Engineering, Biochemical Engineering, Biochemistry, Data Science, Computer Science, Biomedical Engineering, Applied Mathematics, Analytical Chemistry, Physics, Software Engineering, or a related quantitative field.
    • A minimum cumulative GPA of 3.0 on a 4.0 scale.
    • Foundational knowledge of mRNA technology or biopharmaceutical manufacturing.
    • Experience developing physics-informed, physics-constrained, first-principle, or hybrid dynamic models.
    • Proficiency in Python, with additional experience in MATLAB, Julia, or gPROMS considered a plus.
    • Familiarity with Design of Experiments, uncertainty quantification, and Bayesian optimization.
    • Strong written and verbal communication skills.
    • Permanent authorization to work in the U.S. without the need for visa sponsorship.

    Location & details#

    • Location: Waltham, Massachusetts
    • Term: Winter 2027
    • Duration: 6 months
    • Commitment: Full-time, 40 hours per week, Monday to Friday
    • Work Modality: On-site
    • Compensation: $35.00 to $60.00 hourly, determined by experience

    About Sanofi

    Sanofi is a pharmaceutical manufacturing company based in Paris, France. It employs over 93,000 people across global offices. The company focuses on vaccines, rare diseases, neurology, immunology, and oncology. It also operates in the fields of diabetes, cardiovascular diseases, and consumer healthcare.

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