Functional Genomics Co-op

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    Vertex Pharmaceuticals

    5,001-10,000 employeesFounded 1989Boston, MABiotechnology Research
    Actively hiringPaidWinter 2027Biotechnology Research
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    About the role#

    The Functional Genomics Co-op is a 6-month experiential training program designed for students pursuing an advanced degree. You will join the Research functional area to support small-molecule drug discovery programs through genomic technologies, including CRISPR-Cas9 gene editing and high-throughput genetic screening. This role offers the opportunity to contribute to target validation and mechanism-of-action studies while working alongside scientists to advance therapeutic programs.

    What you'll do#

    • Contribute to study planning and oversee experimental activities based on established protocols.
    • Collaborate with scientists to conduct experiments using disease-relevant human cell models.
    • Generate gene-edited cellular models and develop disease-relevant assays.
    • Perform cellular screening experiments and evaluate compound activity using flow cytometry and high-content imaging.
    • Analyze experimental data to guide project decisions and summarize key findings.
    • Maintain accurate records of methods, observations, and results in an electronic laboratory notebook.
    • Present results and conclusions to the Functional Genomics team and project partners.

    What you'll need#

    • Current enrollment in a master's degree or PhD program in Biology, Biochemistry, Genetics, Computational Biology, or a related scientific discipline.
    • If graduating before June 2027, you must be enrolled in an advanced degree program.
    • Hands-on experience with human cell culture or tissue culture.
    • Familiarity with molecular biology methods, specifically PCR and cloning.
    • Foundational understanding of genetics, genomics, and gene-editing technologies.
    • Experience with flow cytometry is highly preferred.
    • Experience with CRISPR-Cas9 gene editing is preferred.
    • Experience generating, maintaining, and characterizing mammalian cell lines is preferred.

    Location & details#

    • Location: Boston, Massachusetts.
    • Term: Winter 2027 (January to June 2027).
    • Modality: On-site, full-time (40 hours per week).
    • Compensation: $30.00 - $40.00 per hour.
    • Note: This is a paid position. Sponsorship is not provided.

    About Vertex Pharmaceuticals

    Vertex Pharmaceuticals is a biotechnology company founded in 1989. It focuses on scientific research to develop medicines for serious diseases such as cystic fibrosis, sickle cell disease, and various forms of pain. The company maintains its global headquarters in Boston and operates research and commercial sites across the globe. It employs between 5,001 and 10,000 people.

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